Thông tin cho nhân viên y tế
Thuốc mới và thông tin từ Drugs.com
- On January 22, 2025, Medexus was informed that the FDA approved Grafapex, an alkylating agent, with fludarabine as a preparative regimen for allogeneic hematopoietic stem cell transplantation (alloHSCT) in adult and pediatric patients one year of…
- Titusville, New Jersey, January 21, 2025 – Johnson & Johnson (NYSE: JNJ) announced today the U.S. Food and Drug Administration (FDA) approval of a supplemental New Drug Application (sNDA) for Spravato (esketamine) CIII nasal spray, making…
- WILMINGTON, Del.– January 17, 2025 — Datroway (datopotamab deruxtecan-dlnk) has been approved in the US for the treatment of adult patients with unresectable or metastatic hormone receptor (HR)-positive, HER2-negative (IHC 0, IHC 1+ or IHC…
- 17 January 2025 — AstraZeneca’s Calquence (acalabrutinib) in combination with bendamustine and rituximab has been approved in the US for the treatment of adult patients with previously untreated mantle cell lymphoma (MCL) who are ineligible…
- THOUSAND OAKS, Calif., Jan. 17, 2025 /PRNewswire/ — Amgen (NASDAQ:AMGN) today announced that the U.S. Food and Drug Administration (FDA) has approved Lumakras (sotorasib) in combination with Vectibix (panitumumab) for the treatment of adult…
- INDIANAPOLIS, Jan. 15, 2025 /PRNewswire/ — Eli Lilly and Company (NYSE: LLY) announced today that the U.S. Food and Drug Administration (FDA) has approved Omvoh (mirikizumab-mrkz) for the treatment of moderately to severely active Crohn's disease…
- FRIDAY, Jan. 24, 2025 — In a clinical guideline issued by the American College of Gastroenterology and published in the January issue of the American Journal of Gastroenterology, recommendations are presented for the diagnosis and management of…
- FRIDAY, Jan. 24, 2025 — Diagnoses of sedative, hypnotic, or anxiolytic use disorders (SHA-UD) increased threefold to fivefold between 2001 and 2019 for adolescent and young adult U.S. Medicaid enrollees, according to a study published online Jan…
- FRIDAY, Jan. 24, 2025 — Physiological metrics from wearable devices can help identify inflammatory bowel disease (IBD) flares, according to a study published online Jan. 16 in Gastroenterology. Robert P. Hirten, M.D., from the Icahn School of…
- FRIDAY, Jan. 24, 2025 — Incorporating multiparametric magnetic resonance imaging (mpMRI) for initial staging can reduce the time to correct treatment (TTCT) for patients with muscle-invasive bladder cancer (MIBC), according to a study published…
- FRIDAY, Jan. 24, 2025 — Adults with sickle cell anemia (SCA) and healthy controls with greater economic deprivation have older brain age, according to a study published online Jan. 17 in JAMA Network Open. Andria L. Ford, M.D., from Washington…
- FRIDAY, Jan. 24, 2025 — For patients with newly diagnosed multiple myeloma (NDMM) receiving dexamethasone induction, dose reductions do not negatively impact survival, according to a study published online Jan. 2 in Blood. Rahul Banerjee, M.D…
Thông tin từ The Pharma Letter
- Denmark’s Novo Nordisk saw its shares rise as much as 13% to 659.20 kroner this morning, after it announced top-line results from a Phase Ib/IIa clinical trial with amycretin once weekly subcutaneous (SC) administration.
- US vaccines developer Moderna today announced that it has been awarded a tender for the supply of its mRNA COVID-19 vaccine in the European Union (EU), Norway and North Macedonia.
- The UK’s Medicines and Healthcare products Regulatory Agency (MHRA) has today approved garadacimab (brand name Andembry) for patients aged 12 years and older with hereditary angioedema (HAE) to prevent angioedema attacks.
- Neurocrine Biosciences has announced the appointment of Andrew Ratz as senior VP of drug development, supporting the firm’s expanding R&D efforts.
- New Jerseyan biopharmaceutical company Tris Pharma has announced encouraging top-line data from its Phase III ALLEVIATE-1 trial testing cebranopadol as an option for acute pain.
- Spreading its geographic wings further, in the face of ongoing difficulties in China, UK pharma major AstraZeneca has announced a C$820 million (US$570 million) investment in Canada, creating more than 700 high-skilled jobs, across all areas of the business.
Thông tin từ BioPharmaDive
- Brenner, who has worked in the FDA’s Center for Devices and Radiological Health, will lead the agency until a permanent commissioner is confirmed.
- An experimental drug called amycretin showed signs it could be more potent than Eli Lilly’s rival Zepbound, though analysts cautioned certain aspects of the study may have inflated its performance.
- The Trump administration is bringing new instability to a sector already grappling with a shaky market as well as threats like competition from China.
- Merck and Eisai reported new data for a drug regimen of Keytruda and Lenvima. Elsewhere, AstraZeneca expanded in Canada and the FDA delayed a decision on Stealth’s Barth treatment.
- The China-based drug developer’s offering will fund testing of medicines for several blood malignancies — one of which is part of an alliance with Takeda.
- The Senate Finance Committee will meet on Jan. 29 to discuss the confirmation of RFK Jr., whose stances on vaccines and abortion have raised questions from Democrats and Republicans alike.
Thông tin từ STAT News
- The Trump administration's freeze on communications, travel, and diversity efforts has sowed chaos across federal health agencies.
- The Trump administration has appointed Matthew Memoli, a veteran researcher who was critical of the U.S. response to the Covid pandemic, as acting head of the NIH.
- From new hires to departures, promotions and transfers, here are the latest comings and goings in the pharmaceutical industry.
- President Trump has ended the federal security detail for Anthony Fauci, the infectious disease expert who advised him on the Covid-19 pandemic.
- The decision comes as Trump paused some federal work and could help UnitedHealth generate bigger profits from the taxpayer-funded program.
- Biogen CEO told Massachusetts Gov. Maura Healey this week he’s concerned about "a lot more policy risk" in D.C.
Thông tin từ Nature Review Drug Discovery
- Nature Reviews Drug Discovery, Published online: 22 January 2025; doi:10.1038/d41573-025-00016-yBase editing reduces prion protein
- Nature Reviews Drug Discovery, Published online: 22 January 2025; doi:10.1038/d41573-025-00015-zJ&J buys Intra-Cellular Therapies for US$14.6 billion, expanding its neuroscience portfolio
- Nature Reviews Drug Discovery, Published online: 17 January 2025; doi:10.1038/d41573-025-00014-02024 FDA approvals exceed average number but have lower sales projections
- Nature Reviews Drug Discovery, Published online: 15 January 2025; doi:10.1038/d41573-025-00012-2Oncology innovations, obesity medicines, an uptick for mergers and acquisitions, regulation for artificial intelligence applications and growing consumerization are expected to be key topics.
- Nature Reviews Drug Discovery, Published online: 15 January 2025; doi:10.1038/d41573-025-00013-1Biopharma dealmaking in 2024
- Nature Reviews Drug Discovery, Published online: 14 January 2025; doi:10.1038/s41573-024-01105-0Impaired mitophagy leading to the accumulation of damaged mitochondria is associated with the onset and progression of neurodegenerative diseases. This Review provides an overview of the molecular pathways of mitophagy regulation in neurons, discusses evidence implicating mitophagy impairment in the pathogenesis of neurodegenerative diseases and assesses […]